Gather all ingredients and chop vegetables.

In a large bowl, mix ground beef with salt and pepper gently. Shape into four patties about 1 inch thick, creating a small indentation in the center.

Preheat grill or skillet to medium-high heat. Cook patties for about 4 minutes on one side until browned; flip and cook another 3 minutes.

Add cheese slices on top of each patty during the last minute of cooking to melt.

Toast burger buns lightly on the grill.

Assemble burgers by placing each patty on the bottom bun and layering with lettuce, tomato, pickles, ketchup, mustard, and other desired toppings.